Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]propane-1-sulfonamide
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 PubChem ID
CID: 11632731
SID: 16735896
Canonical SMILES
CC1(C)N(CCCS(N)(=O)=O)C(=S)N(C1=O)c1ccc(C#N)c(Cl)c1
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Compound Formula C15H17ClN4O3S2
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 440 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CL000141 LNCaP
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
2
IC50 = 12 nM
   TI
   LI
   LO
   TS
3
IC50 = 410 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 440 nM