Brief Information of the Compound and Protein
Compound Name
 Compound Info 
bicyclic sulfonamide analogue, 14
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 PubChem ID
CID: 44143276
Canonical SMILES
CCNc1cc(cc2N(C)S(=O)(=O)CCCc12)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1CCOCC1
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Compound Formula C28H40N4O5S
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1185 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 190 nM