Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2-fluoro-4-(trifluoromethyl)phenyl)-3-(3-(5-(3-(piperazine-1-carbonyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)urea
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 PubChem ID
CID: 45267792
Canonical SMILES
CN1CCN(CC1)C(=O)c1cccc(c1)-c1cnc2[nH]cc(-c3cccc(NC(=O)Nc4ccc(cc4F)C(F)(F)F)c3)c2c1
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Compound Formula C33H28F4N6O2
Compound Structure
Protein Name
 Protein Info 
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 335 nM
   TI
   LI
   LO
   TS