Brief Information of the Compound and Protein
Compound Name
1-Methyl-8-{[3-(trifluoromethyl)phenyl]amino}-4,5-dihydro-1Hpyrazolo[4,3-h]quinazoline-3-carboxamide
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PubChem ID
CID: 46886878
Canonical SMILES
Cn1nc(C(N)=O)c2CCc3cnc(Nc4cccc(c4)C(F)(F)F)nc3-c12
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Compound Formula C18H15F3N6O
Compound Structure
Protein Name
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 51 nM
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