Brief Information of the Compound and Protein
Compound Name
pyrazolo[4,3-h]quinazoline-3-carboxamide, 1
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PubChem ID
CID: 44236351
SID: 85255644
Canonical SMILES
Cn1nc(C(N)=O)c2CCc3cnc(Nc4ccccc4)nc3-c12
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Compound Formula C17H16N6O
Compound Structure
Protein Name
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 68 nM