Brief Information of the Compound and Protein
Compound Name
3-[(1R)-1-[5-[3,5-dichloro-2-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-3-fluoropyridin-2-yl]ethyl]-1-ethyl-1-[(2,2,2-trifluoroacetyl)amino]urea
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PubChem ID
CID: 46230162
Canonical SMILES
CCN(NC(=O)C(F)(F)F)C(=O)N[C@H](C)c1ncc(cc1F)-c1cc(Cl)cc(Cl)c1-c1noc(C)n1
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Compound Formula C21H18Cl2F4N6O3
Compound Structure
Protein Name
B1 bradykinin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Bradykinin receptor
Uniprot ID
P46663
Gene Name
BDKRB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000411 IMR-90 Homo sapiens (Human)  1
1
IC50 = 1.3 nM
   TI
   LI
   LO
   TS