Brief Information of the Compound and Protein
Compound Name
4-(4-Isopropyl-phenyl)-1-(3-methyl-benzyl)-6-propargyloxy-1H-quinazolin-2-one
    Show/Hide
PubChem ID
CID: 45140794
SID: 92390737
Canonical SMILES
CC(C)c1ccc(cc1)-c1nc(=O)n(Cc2cccc(C)c2)c2ccc(OCC#C)cc12
    Show/Hide
Compound Formula C28H26N2O2
Compound Structure
Protein Name
Extracellular calcium-sensing receptor
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Ion receptor (family C GPCR)
>
Calcium sensing receptor
>
Calcium sensing receptor
Uniprot ID
P41180
Gene Name
CASR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000351 Dede Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1.8 nM
   TI
   LI
   LO
   TS