Brief Information of the Compound and Protein
Compound Name
1-(3,5-Bis-trifluoromethylphenyl)-3-[3-(4-chloro-2-methyl-2Hpyrazol-3-yl)-4-methoxyphenyl]urea
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PubChem ID
CID: 11363880
SID: 16456365
Canonical SMILES
COc1ccc(NC(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1-c1c(Cl)cnn1C
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Compound Formula C20H15ClF6N4O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 3.981 nM
   TI
   LI
   LO
   TS
2
Ki = 1 nM
   TI
   LI
   LO
   TS