Brief Information of the Compound and Protein
Compound Name
Anilinoquinazoline deriv. 4
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PubChem ID
CID: 5329006
SID: 15646968
Canonical SMILES
COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC
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Compound Formula C16H13ClFN3O2
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P17948
Gene Name
FLT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000073 A-498 Homo sapiens (Human)  2
1
IC50 = 14100 nM
   TI
   LI
   LO
   TS
2
IC50 = 17700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2000 nM
2 IC50 = 17700 nM