Brief Information of the Compound and Protein
Compound Name
(Z)-N-[3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-2-oxo-2,3-dihydro-1H-indol-5-yl]-4-(4-methyl-piperazin-1-ylmethyl)-benzamide
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PubChem ID
CID: 46233183
Canonical SMILES
CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc3NC(=O)\C(=C/c4[nH]c(C)cc4C)c3c2)CC1
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Compound Formula C28H31N5O2
Compound Structure
Protein Name
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 5900 nM
   TI
   LI
   LO
   TS