Brief Information of the Compound and Protein
Compound Name
(3S,5S)-5-[(E)-2-cyclopropylethenyl]-3-ethyl-6,7-difluoro-5-(trifluoromethyl)-1H-4,1-benzoxazepin-2-one
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PubChem ID
CID: 16220269
SID: 24902676
Canonical SMILES
CC[C@@H]1O[C@@](\C=C\C2CC2)(c2c(F)c(F)ccc2NC1=O)C(F)(F)F
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Compound Formula C17H16F5NO2
Compound Structure
Protein Name
Parathyroid hormone/parathyroid hormone-related peptide receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Parathyroid hormone receptor
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Parathyroid hormone receptor
Uniprot ID
Q03431
Gene Name
PTH1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000787 HKRK-B28 Sus scrofa (Pig)  3
1
IC50 = 990 nM
   TI
   LI
   LO
   TS
2
IC50 = 5780 nM
   TI
   LI
   LO
   TS
3
IC50 = 68000 nM
   TI
   LI
   LO
   TS