Brief Information of the Compound and Protein
Compound Name
4-chloro-N-(2,3-dihydro-1H-inden-2-ylmethyl)-3-ethyl-1-methylpyrazolo[3,4-b]pyridine-5-carboxamide
    Show/Hide
PubChem ID
CID: 46883893
Canonical SMILES
CCc1nn(C)c2ncc(C(=O)NCC3Cc4ccccc4C3)c(Cl)c12
    Show/Hide
Compound Formula C20H21ClN4O
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  2
1
EC50 > 6309.57 nM
   TI
   LI
   LO
   TS
2
IC50 = 251.19 nM
   TI
   LI
   LO
   TS