Brief Information of the Compound and Protein
Compound Name
2-(4-(Pyridin-2-yl)phenyl)-1H-benzo[d]imidazole-4-carboxamide
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PubChem ID
CID: 44542366
SID: 87224005
Canonical SMILES
NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccccn1
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Compound Formula C19H14N4O
Compound Structure
Protein Name
Poly [ADP-ribose] polymerase 1
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P09874
Gene Name
PARP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000337 C-4-I Homo sapiens (Human)  2
1
EC50 = 7.8 nM
   TI
   LI
   LO
   TS
2
EC50 = 8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 83 nM
2 Ki = 1.9 nM
3 Ki = 2 nM