Brief Information of the Compound and Protein
Compound Name
4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]-2-methoxypyrimidine
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PubChem ID
CID: 9863367
SID: 14827882
Canonical SMILES
COc1nccc(n1)-c1c(ncn1C1CCNCC1)-c1ccc(F)cc1
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Compound Formula C19H20FN5O
Compound Structure
Protein Name
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000293 HLF Homo sapiens (Human)  1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19 nM
2 IC50 = 40 nM
3 Ki = 36 nM