Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-cyclopropylamide 4'-cyclopropylmethyl-amide
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 PubChem ID
CID: 24856363
SID: 56260871
Canonical SMILES
Cc1ccc(cc1-c1ccc(cc1)C(=O)NCC1CC1)C(=O)NC1CC1
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Compound Formula C22H24N2O2
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000293 HLF
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 75 nM
2 IC50 = 199.53 nM
3 IC50 = 1584.89 nM
4 Ki = 9 nM
5 Ki = 10 nM
6 Ki = 12 nM
7 Ki = 12.59 nM