Brief Information of the Compound and Protein
Compound Name
4-(5,6-dihydrothieno[2,3-h]quinazolin-2-ylamino)-N-(3-(dimethylamino)propyl)benzenesulfonamide
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PubChem ID
CID: 46890388
Canonical SMILES
CN(C)CCCNS(=O)(=O)c1ccc(Nc2ncc3CCc4sccc4-c3n2)cc1
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Compound Formula C21H25N5O2S2
Compound Structure
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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Other protein kinase group
Uniprot ID
O14920
Gene Name
IKBKB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 620 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 780 nM