Brief Information of the Compound and Protein
Compound Name
2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
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PubChem ID
CID: 46889696
SID: 121272449
Canonical SMILES
CN(C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cnc(cc1-c1ccccc1Cl)N1C[C@H](O)C[C@H]1CO
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Compound Formula C29H28ClF6N3O3
Compound Structure
Protein Name
Neuromedin-K receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
Ki = 1.12 nM
   TI
   LI
   LO
   TS