Brief Information of the Compound and Protein
Compound Name
4-Hydroxy-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[e][1,2]thiazine-3-carboxylic acid[6-(3,4-dichloro-phenyl)-pyridin-3-yl]-amide
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PubChem ID
CID: 54728419
Canonical SMILES
OC1=C(NS(=O)(=O)c2ccccc12)C(=O)Nc1ccc(nc1)-c1ccc(Cl)c(Cl)c1
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Compound Formula C20H13Cl2N3O4S
Compound Structure
Protein Name
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000390 FF Mesocricetus auratus (Golden hamster)  1
1
IC50 = 690 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 160 nM