Brief Information of the Compound and Protein
Compound Name
N-[3-fluoro-4-[7-methoxy-6-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2-oxoimidazolidine-1-carboxamide
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PubChem ID
CID: 24965938
SID: 56264059
Canonical SMILES
COc1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccc(F)cc4)cc3F)c2cc1OCCCN1CCOCC1
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Compound Formula C33H33F2N5O6
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 30 nM