Brief Information of the Compound and Protein
Compound Name
(S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpropan-2-ylamino)propoxy)-1H-benzo[d]imidazol-2(3H)-one
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PubChem ID
CID: 44583033
Canonical SMILES
COc1ccc(CC(C)(C)NC[C@H](O)COc2cccc3[nH]c(=O)[nH]c23)cc1
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Compound Formula C21H27N3O4
Compound Structure
Protein Name
Extracellular calcium-sensing receptor
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Ion receptor (family C GPCR)
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Calcium sensing receptor
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Calcium sensing receptor
Uniprot ID
P41180
Gene Name
CASR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
2
IC50 = 31.8 nM
   TI
   LI
   LO
   TS