Brief Information of the Compound and Protein
Compound Name
4-(2,3-dihydro-1H-inden-2-yloxy)-6-(piperazin-1-yl)-N-(pyridin-4-yl)-1,3,5-triazin-2-amine
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PubChem ID
CID: 45483210
Canonical SMILES
C1C(Cc2ccccc12)Oc1nc(Nc2ccncc2)nc(n1)N1CCNCC1
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Compound Formula C21H23N7O
Compound Structure
Protein Name
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 57 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM