Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(3-methylpiperazin-1-yl)-N4-(pyridin-4-yl)-1,3,5-triazine-2,4-diamine
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 PubChem ID
CID: 45483285
SID: 96027632
Canonical SMILES
C[C@@H]1CN(CCN1)c1nc(NC2Cc3ccccc3C2)nc(Nc2ccncc2)n1
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Compound Formula C22H26N8
Compound Structure
Protein Name
 Protein Info 
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM