Brief Information of the Compound and Protein
Compound Name
7-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrolo[2,3-d]pyridazine-2-carboxamide
    Show/Hide
PubChem ID
CID: 46879474
Canonical SMILES
Fc1cccc(COc2ccc(Nc3nncc4cc([nH]c34)C(=O)NCCN3CCCC3)cc2Cl)c1
    Show/Hide
Compound Formula C26H26ClFN6O2
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000261 SK-BR-3 Homo sapiens (Human)  1
1
IC50 = 620 nM
   TI
   LI
   LO
   TS