Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2-(diethylamino)ethyl)-3-methyl-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide
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 PubChem ID
CID: 24786207
SID: 49710620
Canonical SMILES
CCN(CC)CCNC(=O)c1[nH]c2cnnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1C
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Compound Formula C27H30ClFN6O2
Compound Structure
Protein Name
 Protein Info 
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000261 SK-BR-3
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 960 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM