Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 12
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 PubChem ID
CID: 25218604
Canonical SMILES
COc1cc(ccc1Nc1nc(Nc2cc(F)ccc2C(N)=O)c2cc[nH]c2n1)N1CCOCC1
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Compound Formula C24H24FN7O3
Compound Structure
Protein Name
 Protein Info 
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.6 nM
   TI
   LI
   LO
   TS