Brief Information of the Compound and Protein
Compound Name
1-(2-fluoroethyl)-3-(4-(4-morpholino-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)urea
    Show/Hide
PubChem ID
CID: 44606131
SID: 87355861
Canonical SMILES
FCCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(CC(F)(F)F)c2n1
    Show/Hide
Compound Formula C20H21F4N7O2
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
>
Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.6 nM