Brief Information of the Compound and Protein
Compound Name
2-(2-(dimethylamino)-3-phenyl-3,4-dihydroquinazolin-4-yl)-N-(4-nitrobenzyl)acetamide
    Show/Hide
PubChem ID
CID: 44567629
Canonical SMILES
CN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccc(cc2)[N+]([O-])=O)N1c1ccccc1
    Show/Hide
Compound Formula C25H25N5O3
Compound Structure
Protein Name
Voltage-dependent T-type calcium channel subunit alpha-1G
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Voltage-gated calcium channel
Uniprot ID
O43497
Gene Name
CACNA1G
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 349.95 nM
   TI
   LI
   LO
   TS
2
IC50 = 350 nM
   TI
   LI
   LO
   TS