Brief Information of the Compound and Protein
Compound Name
N-benzyl-2-[2-[5-(dimethylamino)pentyl-methylamino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetamide
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PubChem ID
CID: 23661603
SID: 46535086
Canonical SMILES
CN(C)CCCCCN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(cc1)-c1ccccc1
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Compound Formula C37H43N5O
Compound Structure
Protein Name
Voltage-dependent T-type calcium channel subunit alpha-1G
Protein Classification
Ion channel
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Voltage-gated ion channel
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Voltage-gated calcium channel
Uniprot ID
O43497
Gene Name
CACNA1G
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
2
IC50 = 41.3 nM
   TI
   LI
   LO
   TS
3
IC50 = 260 nM
   TI
   LI
   LO
   TS
CL000027 tsA201 Homo sapiens (Human)  1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS