Brief Information of the Compound and Protein
Compound Name
1-(4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-3-(2-nitrophenyl)urea
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PubChem ID
CID: 44565459
Canonical SMILES
COc1cc2CCN(CCc3ccc(NC(=O)Nc4ccccc4[N+]([O-])=O)cc3)Cc2cc1OC
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Compound Formula C26H28N4O5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000756 MCF/MX Homo sapiens (Human)  1
1
IC50 = 10200 nM
   TI
   LI
   LO
   TS
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 = 9080 nM
   TI
   LI
   LO
   TS