Brief Information of the Compound and Protein
Compound Name
1-(2-Aminophenyl)-3-(4-(2-(3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)urea
    Show/Hide
PubChem ID
CID: 44565482
Canonical SMILES
Nc1ccccc1NC(=O)Nc1ccc(CCN2CCc3ccccc3C2)cc1
    Show/Hide
Compound Formula C24H26N4O
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 = 74100 nM
   TI
   LI
   LO
   TS