Brief Information of the Compound and Protein
Compound Name
6-(3-(4-(3,4-dichlorophenoxy)piperidin-1-yl)propylamino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
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PubChem ID
CID: 22322323
Canonical SMILES
Cn1c(NCCCN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)cc(=O)n(C)c1=O
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Compound Formula C20H26Cl2N4O3
Compound Structure
Protein Name
Histamine H1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 58 nM