Brief Information of the Compound and Protein
Compound Name
(2R)-2-[4-[1-[cyclopropyl-(4-pyridin-2-ylcyclohexyl)amino]ethenyl]phenyl]-1,1,1-trifluoropropan-2-ol
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Canonical SMILES
C[C@@](O)(c1ccc(cc1)C(=C)N(C1CC1)[C@H]1CC[C@H](CC1)c1ccccn1)C(F)(F)F
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Compound Formula C25H29F3N2O
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 1.6 nM
   TI
   LI
   LO
   TS