Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEMBL2021498
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Canonical SMILES
C[C@@](O)(c1ccc(cc1)C(=O)N(C1CC1)[C@H]1CC[C@@](CC1)(C#N)c1ccccn1)C(F)(F)F
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Compound Formula C25H26F3N3O2
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 39 nM
   TI
   LI
   LO
   TS
2
IC50 > 300 nM
   TI
   LI
   LO
   TS