Brief Information of the Compound and Protein
Compound Name
4-amino-N-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)benzamide
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PubChem ID
CID: 44451563
Canonical SMILES
COc1cc2CCN(CCc3ccc(NC(=O)c4ccc(N)cc4)cc3)Cc2cc1OC
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Compound Formula C26H29N3O3
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780 Homo sapiens (Human)  2
1
IC50 = 4073.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 7079.46 nM
   TI
   LI
   LO
   TS
CL000135 A2780ADR Homo sapiens (Human)  1
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS