Brief Information of the Compound and Protein
Compound Name
N-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]quinoline-3-carboxamide
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PubChem ID
CID: 44451912
Canonical SMILES
O=C(Nc1ccc(CCN2CCc3ccccc3C2)cc1)c1cnc2ccccc2c1
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Compound Formula C27H25N3O
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780 Homo sapiens (Human)  2
1
IC50 = 416.87 nM
   TI
   LI
   LO
   TS
2
IC50 = 524.81 nM
   TI
   LI
   LO
   TS
CL000135 A2780ADR Homo sapiens (Human)  1
1
IC50 = 430 nM
   TI
   LI
   LO
   TS