Brief Information of the Compound and Protein
Compound Name
(cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
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PubChem ID
CID: 11044358
SID: 16109792
Canonical SMILES
COc1ccc(cc1OC)C1=NNC(=O)[C@@H]2CC=CC[C@H]12
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Compound Formula C16H18N2O3
Compound Structure
Protein Name
3',5'-cyclic-AMP phosphodiesterase 4D
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 4
>
Phosphodiesterase 4D
Uniprot ID
Q08499
Gene Name
PDE4D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 213 nM