Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1H-indole-5-carbonitrile
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 PubChem ID
CID: 11310988
SID: 16399932
Canonical SMILES
CN(C)C[C@H]1C[C@@H]1c1c[nH]c2ccc(cc12)C#N
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Compound Formula C15H17N3
Compound Structure
Protein Name
 Protein Info 
Sodium-dependent serotonin transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P31645
Gene Name
SLC6A4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 0.36 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.56 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.48 nM
2 Ki = 0.18 nM
3 Ki = 0.56 nM