Brief Information of the Compound and Protein
Compound Name
3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)quinazolin-4(3H)-one
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PubChem ID
CID: 11581337
SID: 16683781
Canonical SMILES
Cn1c(nc2ccccc2c1=O)-c1ccc(OCCCN2CCCC2)cc1
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Compound Formula C22H25N3O2
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
P58406
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 9.6 nM
   TI
   LI
   LO
   TS
2
Ki = 2.4 nM
   TI
   LI
   LO
   TS