Brief Information of the Compound and Protein
Compound Name
trans-5-(2-(1H-pyrazol-4-yl)vinyl)-N-(1-(3-amino-3-oxopropyl)-5-(N-methylbenzamido)-1H-benzo[d]imidazol-2(3H)-ylidene)thiophene-2-carboxamide
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PubChem ID
CID: 25169252
SID: 57275092
Canonical SMILES
CN(C(=O)c1ccccc1)c1ccc2c(c1)[nH]/c(=N\C(=O)c1ccc(/C=C/c3cn[nH]c3)s1)n2CCC(N)=O
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Compound Formula C28H25N7O3S
Compound Structure
Protein Name
Tyrosine-protein kinase ITK/TSK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q08881
Gene Name
ITK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000302 DT40 Gallus gallus (Chicken)  1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9 nM