Brief Information of the Compound and Protein
Compound Name
(E)-N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-3-phenyl-acrylamide
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PubChem ID
CID: 5475158
SID: 14827182
Canonical SMILES
CN(C)CCCSc1ccccc1NC(=O)\C=C\c1ccccc1
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Compound Formula C20H24N2OS
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  2
1
Ki = 17 nM
   TI
   LI
   LO
   TS
2
Ki = 24 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 13 nM
   TI
   LI
   LO
   TS
2
Ki = 22 nM
   TI
   LI
   LO
   TS