Brief Information of the Compound and Protein
Compound Name
1-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(3,4,5-trimethoxy-phenyl)-acetyl]-pyrrolidin-3-yl}-ethyl)-4-phenyl-piperidine-4-carboxylic acid amide
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PubChem ID
CID: 44385575
Canonical SMILES
COc1cc(CC(=O)N2CCC(CCN3CCC(CC3)(C(N)=O)c3ccccc3)(C2)c2ccc(Cl)c(Cl)c2)cc(OC)c1OC
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Compound Formula C35H41Cl2N3O5
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 66.2 nM
   TI
   LI
   LO
   TS