Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-amino-1-(2,4-difluorophenyl)-N-[2-[(1-ethyl-3,4-dihydro-2H-naphthalen-1-yl)methyl]-3,3,3-trifluoro-2-hydroxypropyl]pyrazole-4-carboxamide
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 PubChem ID
CID: 44433500
Canonical SMILES
CCC1(CC(O)(CNC(=O)c2cnn(c2N)-c2ccc(F)cc2F)C(F)(F)F)CCCc2ccccc12
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Compound Formula C26H27F5N4O2
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 < 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.677 nM