Brief Information of the Compound and Protein
Compound Name
5-methyl-1-phenyl-N-[3,3,3-trifluoro-2-hydroxy-2-[(1-methyl-3,4-dihydro-2H-naphthalen-1-yl)methyl]propyl]pyrazole-4-sulfonamide
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PubChem ID
CID: 44433486
Canonical SMILES
Cc1c(cnn1-c1ccccc1)S(=O)(=O)NCC(O)(CC1(C)CCCc2ccccc12)C(F)(F)F
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Compound Formula C25H28F3N3O3S
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  3
1
EC50 < 1000 nM
   TI
   LI
   LO
   TS
2
IC50 = 309.03 nM
   TI
   LI
   LO
   TS
3
IC50 < 1000 nM
   TI
   LI
   LO
   TS