Brief Information of the Compound and Protein
Compound Name
5-amino-N-[2-[(1-cyclopentyl-3,4-dihydro-2H-naphthalen-1-yl)methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxamide
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PubChem ID
CID: 44433501
Canonical SMILES
Nc1c(cnn1-c1ccc(F)cc1F)C(=O)NCC(O)(CC1(CCCc2ccccc12)C1CCCC1)C(F)(F)F
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Compound Formula C29H31F5N4O2
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 275.42 nM
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