Brief Information of the Compound and Protein
Compound Name
2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]phenyl}acetic acid
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PubChem ID
CID: 9863447
SID: 14827979
Canonical SMILES
CC(C)c1cc(Oc2c(Cl)cc(CC(O)=O)cc2Cl)ccc1O
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Compound Formula C17H16Cl2O4
Compound Structure
Protein Name
Thyroid hormone receptor alpha
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group A
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Nuclear hormone receptor subfamily 1 group A member 1
Uniprot ID
P10827
Gene Name
THRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 25 nM
2 IC50 = 25.12 nM
3 Ki = 7.18 nM
4 Ki = 7.79 nM