Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(thiophen-2-yl)ethylamino)methyl)phenyl)piperazin-1-yl)propan-2-yl)propanamide
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 PubChem ID
CID: 6918814
SID: 12015883
Canonical SMILES
NCCC(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccccc1CNCCc1cccs1
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Compound Formula C29H35Cl2N5O2S
Compound Structure
Protein Name
 Protein Info 
Melanocortin receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Kd = 12.59 nM
   TI
   LI
   LO
   TS
2
Ki = 1.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.8 nM