Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-{[4-(Methylsulfonyl)piperazin-1-yl]methyl}-N-(5-phenyl-1,3-thiazol-2-yl)pyridin-2-amine
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 PubChem ID
CID: 5329327
SID: 14758742
Canonical SMILES
CS(=O)(=O)N1CCN(Cc2ccnc(Nc3ncc(s3)-c3ccccc3)c2)CC1
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Compound Formula C20H23N5O2S2
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
2
IC50 = 29 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM