Brief Information of the Compound and Protein
Compound Name
5-phenyl-N-[5-(pyrrolidin-1-ylmethyl)pyridin-2-yl]-1,3-thiazol-2-amine
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PubChem ID
CID: 5329324
SID: 16476028
Canonical SMILES
C(N1CCCC1)c1ccc(Nc2ncc(s2)-c2ccccc2)nc1
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Compound Formula C19H20N4S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
2
IC50 = 28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM