Brief Information of the Compound and Protein
Compound Name
1-(3-amino-3-oxopropyl)-2-benzamido-N-cyclohexyl-N-ethyl-1H-benzo[d]imidazole-5-carboxamide
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PubChem ID
CID: 10217158
SID: 15216194
Canonical SMILES
CCN(C1CCCCC1)C(=O)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccccc3)nc2c1
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Compound Formula C26H31N5O3
Compound Structure
Protein Name
Tyrosine-protein kinase ITK/TSK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q08881
Gene Name
ITK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000302 DT40 Gallus gallus (Chicken)  1
1
IC50 = 8100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 390 nM