Brief Information of the Compound and Protein
Compound Name
N-[3-chloro-4-(trifluoromethyl)phenyl]-2-(2-pyridin-4-ylethyl)pyrazole-3-carboxamide
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PubChem ID
CID: 44431911
Canonical SMILES
FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl
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Compound Formula C18H14ClF3N4O
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 95 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 160 nM